Article
Thrombospondin 1 polymorphism associated with decreased expression and increased risk of pterygium.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie - 1 Aug 2021
Simon Lilla S, Keshav Vinny, Baharozian Connor, Masli Sharmila, Lee Hyunjoo J
Abstract excerpt
PURPOSE: To assess the potential association of a thrombospondin 1 gene (THBS1) single-nucleotide polymorphism (rs1478604) with thrombospondin 1 (TSP-1) mRNA expression, as well as the risk of pterygium, in a pilot study. METHODS: DNA and RNA were isolated from peripheral blood samples collected from normal volunteer subjects (n = 39). In addition, DNA was isolated from conjunctival tissue samples collected...
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