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Article

Polymorphism in THBS1 gene is associated with post-refractive surgery chronic ocular surface inflammation.

Ophthalmology - 1 Jul 2014

Contreras-Ruiz Laura, Ryan Denise S, Sia Rose K, Bower Kraig S, Dartt Darlene A, Masli Sharmila

Abstract excerpt

PURPOSE: To determine the association of single nucleotide polymorphisms (SNPs) of the thrombospondin 1 (THBS1) gene with development of chronic ocular surface inflammation (keratoconjunctivitis) after refractive surgery. DESIGN: Retrospective cohort study. PARTICIPANTS: Active duty U.S. Army soldiers (n = 143) who opted for refractive surgery. METHODS: Conjunctival impression cytology samples collected from...

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Identifiers

PMID: 24679443
DOI: 10.1016/j.ophtha.2014.01.033
PMCID: PMC4197802

Genes

THBS1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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