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Impacts of Matrix Metalloproteinase-11 Genotypes on Pterygium Risk.

Anticancer research - 1 Nov 2024

Hsia Ning-Yi, Chen Hung-Chih, Tsai Hung-Wen, Hsia Te-Chun, Hu Pei-Shin, Wang Yun-Chi, Shih Hou-Yu, Chang Wen-Shin, Cheng DA-Chuan, Bau DA-Tian, Tsai Chia-Wen

Abstract excerpt

BACKGROUND/AIM: The dysregulation of matrix metalloproteinase (MMP) proteins has been reported to be involved in the etiology of pterygium. However, studies about the role of matrix metalloproteinase-11 (MMP-11) are lacking. This study is the first to examine the genomic role of MMP-11 in pterygium. MATERIALS AND METHODS: The genotypes of MMP-11 rs738791, rs2267029, rs738792, and rs28382575 were determined in 140...

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PMID: 39477282
DOI: 10.21873/anticanres.17308

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