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Article

Exploring the Contribution of Interleukin-17 Genetic Polymorphisms to Pterygium Risk.

Anticancer research - 1 Mar 2026

Chen Hung-Chih, Hsia Ning-Yi, Hu Pei-Shin, Hsia Te-Chun, Yang Ya-Chen, Chang Wen-Shin, Chao Shih-Chun, Bau DA-Tian, Tsai Chia-Wen

Abstract excerpt

BACKGROUND/AIM: Pterygium is a chronic, fibrovascular ocular surface disorder with tumor-like biological behavior. Although inflammatory mediators such as interleukin-17 (IL17) are increasingly implicated in its pathogenesis, the genetic contribution of IL17 remain unclear. To our knowledge, this study is the first to investigate whether IL17A rs2275913 and IL17F rs763780 polymorphisms influence pterygium...

Topics

Humans
Interleukin-17
Pterygium
Male
Female
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Case-Control Studies

Middle Aged

Taiwan

Genotype

Aged

Risk Factors

Promoter Regions, Genetic

Adult

Gene Frequency

Source

Identifiers

PMID: 41760258
DOI: 10.21873/anticanres.18025

Genes

IL17A
IL17F

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-41760258-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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