Article
Exploring the Genetic Role of Matrix Metalloproteinase-13 Variants in Pterygium Risk.
In vivo (Athens, Greece) - 1 Jan 2025
Chen Hung-Chih, Hsia Ning-Yi, Hu Pei-Shin, Hsia Te-Chun, Wang Yun-Chi, Shih Hou-Yu, Chang Wen-Shin, Bau DA-Tian, Tsai Chia-Wen
Abstract excerpt
BACKGROUND/AIM: Pterygium is a common ocular surface disorder characterized by abnormal fibrovascular growth and extracellular matrix remodeling, yet its precise molecular etiology remains unclear. Matrix metalloproteinases (MMPs) have been implicated in pterygium pathogenesis. However, the genetic contribution of MMP13 remains unexplored. MATERIALS AND METHODS: This case-control study evaluated the association...
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- Humans
- Pterygium
- Male
- Female
- Genetic Predisposition to Disease
- Middle Aged