A Multilevel Functional Study of a SNAP25 At-Risk Variant for Bipolar Disorder and Schizophrenia.

doi:10.1523/JNEUROSCI.1040-17.2017

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Article

A Multilevel Functional Study of a SNAP25 At-Risk Variant for Bipolar Disorder and Schizophrenia.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 25 Oct 2017

Houenou Josselin, Boisgontier Jennifer, Henrion Annabelle, d'Albis Marc-Antoine, Dumaine Anne, Linke Julia, Wessa Michèle, Daban Claire, Hamdani Nora, Delavest Marine, Llorca Pierre-Michel, Lançon Christophe, Schürhoff Franck, Szöke Andrei, Le Corvoisier Philippe, Barau Caroline, Poupon Cyril, Etain Bruno, Leboyer Marion, Jamain Stéphane

Abstract excerpt

The synaptosomal-associated protein SNAP25 is a key player in synaptic vesicle docking and fusion and has been associated with multiple psychiatric conditions, including schizophrenia, bipolar disorder, and attention-deficit/hyperactivity disorder. We recently identified a promoter variant in SNAP25, rs6039769, that is associated with early-onset bipolar disorder and a higher gene expression level in human...

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PMID: 28972123
DOI: 10.1523/JNEUROSCI.1040-17.2017
PMCID: PMC6596626

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SNAP25

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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