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Article

High prevalence of TERT promoter mutations in primary squamous cell carcinoma of the urinary bladder.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 May 2016

Cowan Morgan, Springer Simeon, Nguyen Doreen, Taheri Diana, Guner Gunes, Rodriguez Maria Angelica Mendoza, Wang Yuxuan, Kinde Isaac, VandenBussche Christopher J, Olson Matthew T, Cunha Isabela, Fujita Kazutoshi, Ertoy Dilek, Bivalacqua Trinity J, Kinzler Kenneth, Vogelstein Bert, Netto George J, Papadopoulos Nickolas

Abstract excerpt

TERT promoter mutations (TERT-mut) are detectable in the majority of urothelial carcinomas. The detection of TERT-mut in urine is under investigation as a potential urine-based molecular-screening assay for bladder cancer. A small but significant number of bladder carcinomas are pure squamous cell carcinoma. We sought to assess the incidence of TERT-mut in squamous cell carcinoma of the urinary bladder. A...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Squamous Cell

Share to DNA Mutational Analysis

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Share to Promoter Regions, Genetic

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Source

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Identifiers

PMID: 26965579
DOI: 10.1038/modpathol.2016.53
PMCID: PMC5564297

Genes

TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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