Article
Alcohol and cigarette smoking consumption as genetic proxies for alcohol misuse and nicotine dependence.
Drug and alcohol dependence - 1 Apr 2021
Sanchez-Roige Sandra, Cox Nancy J, Johnson Eric O, Hancock Dana B, Davis Lea K
Abstract excerpt
PURPOSE: To investigate the role of consumption phenotypes as genetic proxies for alcohol misuse and nicotine dependence. METHODS: We leveraged GWAS data from well-powered studies of consumption, alcohol misuse, and nicotine dependence phenotypes measured in individuals of European ancestry from the UK Biobank (UKB) and other population-based cohorts (largest total N = 263,954), and performed genetic correlations...
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