Article
The genetics of alcohol dependence: Twin and SNP-based heritability, and genome-wide association study based on AUDIT scores.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Dec 2015
Mbarek Hamdi, Milaneschi Yuri, Fedko Iryna O, Hottenga Jouke-Jan, de Moor Marleen H M, Jansen Rick, Gelernter Joel, Sherva Richard, Willemsen Gonneke, Boomsma Dorret I, Penninx Brenda W, Vink Jacqueline M
Abstract excerpt
Alcohol dependence (AD) is among the most common and costly public health problems contributing to morbidity and mortality throughout the world. In this study, we investigate the genetic basis of AD in a Dutch population using data from the Netherlands Twin Register (NTR) and the Netherlands Study of Depression and Anxiety (NESDA). The presence of AD was ascertained via the Alcohol Use Disorders Identification...
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