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PCR-Free Methodology for Detection of Single-Nucleotide Polymorphism with a Cationic Polythiophene Reporter.

ACS sensors - 26 Mar 2021

Yucel Muge, Koc Altug, Ulgenalp Ayfer, Akkoc Gun Deniz, Ceyhan Metin, Yildiz Umit Hakan

Abstract excerpt

This study presents a nonamplification-based nucleic acid assay for the detection of single-nucleotide polymorphism (SNP) associated with familial Mediterranean fever (FMF) besides polymerase chain reaction (PCR)-based methodologies. The major objective is to show the potential of the proposed assay for rapid screening of FMF in a Mediterranean region of 400 million population. The assay relies on binding...

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PMID: 33621051
DOI: 10.1021/acssensors.0c02130

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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