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In silico comparison of SARS-CoV-2 spike protein-ACE2 binding affinities across species and implications for virus origin

24 Jun 2021

Abstract excerpt

The devastating impact of the COVID-19 pandemic caused by SARS-coronavirus 2 (SARS-CoV-2) has raised important questions about its origins and the mechanism of its transfer to humans. A further question was whether companion or commercial animals could act as SARS-CoV-2 vectors, with early data suggesting susceptibility is species specific. To better understand SARS-CoV-2 species susceptibility, we undertook an...

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PMID: 34168168
DOI: 10.1038/s41598-021-92388-5

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