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Article

Variants in TNF and NOS3 (eNOS) genes associated with sepsis in adult patients.

The journal of gene medicine - 1 Apr 2021

Özkan Mustafa, Günay Nurullah, Sener Elif Funda, Karcıoglu Özgür, Tahtasakal Reyhan, Dal Fatma, Günay Nahide Ekici, Demiryürek Abdullah Tuncay

Abstract excerpt

BACKGROUND: Sepsis is a life-threatening condition caused by a dysregulated host response to infections and is a leading cause of death in hospitalized patients. The present study aimed to elucidate the possible association between sepsis and the tumor necrosis factor (TNF) gene -308G/A (rs1800629) polymorphism, as well as endothelial nitric oxide synthase (eNOS, NOS3) gene -786T/C (rs2070744), 4a/4b (27 bp-VNTR...

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Identifiers

PMID: 33609421
DOI: 10.1002/jgm.3323

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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