Article
Endothelial nitric oxide synthase 894G→T but not -786T→C gene polymorphism is associated with organ dysfunction and increased mortality in patients with severe sepsis.
The Journal of trauma - 1 Oct 2011
Ma Penglin, Zhu Ying, Qiu Haibo, Liu Jingtao, Wang Yu, Zeng Lin
Abstract excerpt
BACKGROUND: Endothelial nitric oxide synthase (eNOS) -786T→C and 894G→T polymorphisms have been associated with eNOS dysfunction, which might further compromise microcirculatory blood flow during sepsis and increase the risk of organ injury. The purpose of this study is to investigate the association of those two eNOS gene polymorphisms with the severity of organ dysfunction and outcome in patients with severe...
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