Article
[Effect of endothelial nitric oxide synthase gene polymorphisms upon disease severity and outcome in septic patients].
Zhonghua yi xue za zhi - 6 Apr 2010
Zhu Ying, Qiu Hai-bo, Liu Jing-tao, Wang Yu, Lin Hong-yuan, Xu Yuan, Jiang Li, Shi Yan, Zhu Xi, Ning Bo, Cheng Rui, Xie Zhi-yi, Ma Peng-lin
Abstract excerpt
OBJECTIVE: To investigate the association of eNOS 894G-->T, -786T-->C gene polymorphisms with disease severity and outcome in septic patients. METHODS: A total of 117 patients with severe sepsis were randomly selected from ICUs at 9 academic hospitals in Beijing during April 2007 to May 2009. PCR-RFLP and PCR-SSCP were used to analyze the alleles and genotypes in eNOS 894G-->T and -786T--> C gene polymorphisms....
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