Article
Genome-wide association scan for five major dimensions of personality.
Molecular psychiatry - 1 Jun 2010
Terracciano A, Sanna S, Uda M, Deiana B, Usala G, Busonero F, Maschio A, Scally M, Patriciu N, Chen W-M, Distel M A, Slagboom E P, Boomsma D I, Villafuerte S, Sliwerska E, Burmeister M, Amin N, Janssens A C J W, van Duijn C M, Schlessinger D, Abecasis G R, Costa P T
Abstract excerpt
Personality traits are summarized by five broad dimensions with pervasive influences on major life outcomes, strong links to psychiatric disorders and clear heritable components. To identify genetic variants associated with each of the five dimensions of personality we performed a genome-wide association (GWA) scan of 3972 individuals from a genetically isolated population within Sardinia, Italy. On the basis of...
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