Article
Histoplasma capsulatum Glycans From Distinct Genotypes Share Structural and Serological Similarities to Cryptococcus neoformans Glucuronoxylomannan.
Frontiers in cellular and infection microbiology - 1 Jan 2020
Gonçalves Diego de Souza, Rodriguez de La Noval Claudia, Ferreira Marina da Silva, Honorato Leandro, Araújo Glauber Ribeiro de Sousa, Frases Susana, Pizzini Claudia Vera, Nosanchuk Joshua D, Cordero Radames J B, Rodrigues Marcio L, Peralta José Mauro, Nimrichter Leonardo, Guimarães Allan J
Abstract excerpt
The cell wall is a ubiquitous structure in the fungal kingdom, with some features varying depending on the species. Additional external structures can be present, such as the capsule of Cryptococcus neoformans (Cn), its major virulence factor, mainly composed of glucuronoxylomannan (GXM), with anti-phagocytic and anti-inflammatory properties. The literature shows that other cryptococcal species and even more...
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