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Pathogenicity & virulence of Histoplasma capsulatum - A multifaceted organism adapted to intracellular environments

21 Oct 2022

Abstract excerpt

Histoplasmosis is a systemic mycosis caused by the thermally dimorphic fungus Histoplasma capsulatum. Although healthy individuals can develop histoplasmosis, the disease is particularly life-threatening in immunocompromised patients, with a wide range of clinical manifestations depending on the inoculum and virulence of the infecting strain. In this review, we discuss the established virulence factors and...

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PMID: 36266777
DOI: 10.1080/21505594.2022.2137987

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