Article
Breast-conserving therapy for breast cancer with BRCA mutations: a meta-analysis.
Breast cancer (Tokyo, Japan) - 1 Mar 2022
Wang Changjun, Lin Yan, Zhu Hanjiang, Zhou Yidong, Mao Feng, Huang Xin, Zhou Xingtong, Cao Xi, Sun Qiang
Abstract excerpt
BACKGROUND: BRCA1/2 mutated breast cancer accounts for 3 to 12% of all women with breast cancer and significantly increases the lifetime risk of breast cancer. However, the optimal local treatment for breast cancer with BRCA germline mutation remains controversial. Here we present a meta-analysis to evaluate the impact of breast-conserving therapy (BCT) on the prognosis of breast cancer with BRCA mutation....
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