Article
Association of the CD2AP locus with cognitive functioning among middle-aged individuals with a family history of Alzheimer's disease.
Neurobiology of aging - 1 May 2021
Manzali Sigalit Batia, Ravona-Springer Ramit, Alkelai Anna, Yu Eric, Gan-Or Ziv, Ganmore Ithamar, Heymann Anthony, Beeri Michal Schnaider, Greenbaum Lior
Abstract excerpt
First-degree family history is an established risk factor for Alzheimer's disease (AD). We investigated the association of late-onset AD risk loci with cognitive functioning among 315 offspring of AD patients. Participants were cognitively normal Jewish individuals, aged 40-65 years, from the Israel Registry for Alzheimer's Prevention (IRAP) study. Twenty-two single-nucleotide polymorphisms (SNPs) within these...
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