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Article

Human leukocyte antigen (HLA)-G during pregnancy part II: associations between maternal and fetal HLA-G genotypes and soluble HLA-G.

Human immunology - 1 Apr 2015

Dahl Mette, Klitkou Louise, Christiansen Ole B, Djurisic Snezana, Piosik Zofia Maria, Skovbo Peter, Møller Anna Margrethe, Steffensen Rudi, Hviid Thomas Vauvert F

Abstract excerpt

Human leukocyte antigen (HLA)-G is a class Ib molecule with restricted tissue distribution expressed on the extra-villous trophoblast and seems to have immunomodulatory functions during pregnancy. Studies have linked HLA-G polymorphisms to pregnancy complications such as preeclampsia and recurrent miscarriage. Levels of soluble HLA-G (sHLA-G) in blood plasma from non-pregnant donors seem to be associated with...

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PMID: 25637667
DOI: 10.1016/j.humimm.2015.01.015

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