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Article

The maternal HLA-G 1597ΔC null mutation is associated with increased risk of pre-eclampsia and reduced HLA-G expression during pregnancy in African-American women.

Molecular human reproduction - 1 Mar 2013

Loisel Dagan A, Billstrand Christine, Murray Kathleen, Patterson Kristen, Chaiworapongsa Tinnakorn, Romero Roberto, Ober Carole

Abstract excerpt

The non-classical major histocompatibility complex molecule, human leukocyte antigen (HLA)-G, is thought to contribute to maternal immune tolerance and successful placentation during pregnancy. Genetic polymorphisms in HLA-G are known to influence expression levels as well as the relative expression of individual protein isoforms. As diminished or aberrant HLA-G expression patterns may contribute to the...

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Identifiers

PMID: 23002110
DOI: 10.1093/molehr/gas041
PMCID: PMC3579410

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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