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Article

TERT Promoter Mutation Analysis of Whole-Organ Mapping Bladder Cancers.

Genes - 5 Feb 2021

Weyerer Veronika, Eckstein Markus, Strissel Pamela L, Wullweber Adrian, Lange Fabienne, Tögel Lars, Geppert Carol I, Sikic Danijel, Taubert Helge, Wach Sven, Wullich Bernd, Hartmann Arndt, Stoehr Robert, Giedl Johannes

Abstract excerpt

BACKGROUND: Multifocal occurrence is a main characteristic of urothelial bladder cancer (UBC). Whether urothelial transformation is caused by monoclonal events within the urothelium, or by polyclonal unrelated events resulting in several tumor clones is still under debate. TERT promoter mutations are the most common somatic alteration identified in UBC. In this study, we analyzed different histological tissues...

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Share to Neoplasm Recurrence, Local
Share to Biomarkers, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Mutational Analysis

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Share to Promoter Regions, Genetic

Share to Telomerase

Share to Urinary Bladder Neoplasms

Source

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Identifiers

PMID: 33562516
DOI: 10.3390/genes12020230
PMCID: PMC7915609

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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