Article
Small-cell Carcinomas of the Urinary Bladder and Prostate: TERT Promoter Mutation Status Differentiates Sites of Malignancy and Provides Evidence of Common Clonality Between Small-cell Carcinoma of the Urinary Bladder and Urothelial Carcinoma.
European urology focus - 1 Dec 2018
Priemer David S, Wang Mingsheng, Zhang Shaobo, Lopez-Beltran Antonio, Kouba Erik, Montironi Rodolfo, Davidson Darrell D, MacLennan Gregory T, Wang Lisha, Osunkoya Adeboye O, Deng Youping, Emerson Robert E, Cheng Liang
Abstract excerpt
BACKGROUND: Small-cell carcinoma (SCC) of the urinary bladder frequently appears alongside urothelial carcinoma, suggesting common clonality. TERT promoter mutations have been recently implicated in urothelial carcinogenesis. OBJECTIVE: To investigate the degree to which TERT promoter mutations are involved in SCC of the urinary bladder, the linked tumorigenesis between urothelial carcinoma and SCC of the urinary...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.