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Article

Stereotactic Body Radiotherapy Is Effective in Modifying the Tumor Genome and Tumor Immune Microenvironment in Non-Small Cell Lung Cancer or Lung Metastatic Carcinoma.

Frontiers in immunology - 1 Jan 2020

Zhou Pu, Chen Diangang, Zhu Bo, Chen Wei, Xie Qichao, Wang Yali, Tan Qiulin, Yuan Bibo, Zuo Xuejiao, Huang Changlin, Zhu Hongfan, Li Guanghui

Abstract excerpt

Background and Purpose: To directly reveal the change in genome mutation, RNA transcript of tumor cells, and tumor microenvironment (TME) after stereotactic body radiotherapy (SBRT) in paired human lung tumor specimens. Materials and Methods: Paired tumor samples were collected from 10 patients with non-small cell lung cancer (NSCLC) or lung metastatic carcinoma within a week before and after SBRT. DNA and RNA of...

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Identifiers

PMID: 33552051
DOI: 10.3389/fimmu.2020.594212
PMCID: PMC7862546

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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