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Oncogenic Mutations and the Tumor Microenvironment: Drivers of Non-Small Cell Lung Cancer Progression

1 Mar 2025

Abstract excerpt

BACKGROUND/OBJECTIVES: Non-small cell lung cancer (NSCLC) is a major cause of cancer-related deaths globally. The study focuses on understanding the interplay between genetic mutations, cancer stem cells (CSCs), and the tumor microenvironment (TME) in driving NSCLC progression, resistance to therapies, and relapse. METHODS: A systematic search was conducted in PubMed and Scopus databases to identify significant...

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PMID: 40075700
DOI: 10.3390/cancers17050853

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