Article
Immunotherapy for Lung Malignancies: From Gene Sequencing to Novel Therapies.
Chest - 1 Apr 2017
Chee Jonathan, Robinson Bruce W S, Holt Robert A, Creaney Jenette
Abstract excerpt
Harnessing the immune system to fight cancer is an exciting advancement in lung cancer therapy. Antitumor immunity can be augmented by checkpoint blockade therapy, which removes the inhibition/brakes imposed on the immune system by the tumor. Checkpoint blockade therapy with anti-programmed cell death protein 1 (anti-PD-1)/anti-programmed death ligand 1 (anti-PDL-1) antibodies causes tumor regression in about...
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