Article
Reversing insecticide resistance with allelic-drive in Drosophila melanogaster.
Nature communications - 12 Jan 2022
Kaduskar Bhagyashree, Kushwah Raja Babu Singh, Auradkar Ankush, Guichard Annabel, Li Menglin, Bennett Jared B, Julio Alison Henrique Ferreira, Marshall John M, Montell Craig, Bier Ethan
Abstract excerpt
A recurring target-site mutation identified in various pests and disease vectors alters the voltage gated sodium channel (vgsc) gene (often referred to as knockdown resistance or kdr) to confer resistance to commonly used insecticides, pyrethroids and DDT. The ubiquity of kdr mutations poses a major global threat to the continued use of insecticides as a means for vector control. In this study, we generate common...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.