Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Filaggrin expression via immunohistochemistry in basal cell carcinoma and squamous cell carcinoma.

Journal of cutaneous pathology - 1 Jul 2021

Vanderbeck Kaitlin, Orr Christine E, Parvinnejad Nikoo, Wang Tao, Bradshaw Scott, Wang Ami, Asai Yuka

Abstract excerpt

BACKGROUND: Filaggrin is a protein integral to the structure and function of the epidermis. Filaggrin (FLG) loss-of-function (LOF) mutations are common and increase the risk of developing atopic dermatitis (AD) and ichthyosis vulgaris (IV). Epidemiologic data suggest a link between skin cancer and AD. We examined if FLG staining pattern can be used to characterize cutaneous squamous cell carcinomas (SCC), basal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Basal Cell
Share to Dermatitis, Atopic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epidermis

Share to Filaggrin Proteins

Share to Intermediate Filament Proteins

Share to Loss of Function Mutation

Share to Staining and Labeling

Share to Tissue Array Analysis

Source

Identifiers

PMID: 33543489
DOI: 10.1111/cup.13975

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Filaggrin expression via immunohistochemistry in basal cell carcinoma and squamous cell carcinoma.PMID 33543489Read ↗

Filaggrin‐2 barrier protein inversely varies with skin inflammationSemantic proximity Read ↗

Epigenetic Regulation of Filaggrin Gene Expression in Human Epidermal KeratinocytesSemantic proximity Read ↗

Analysis of filaggrin mutations and expression in corneal specimens from patients with or without atopic dermatitis.Semantic proximity Read ↗

Filaggrin loss-of-function mutations and incident cancer: a population-based study.Semantic proximity Read ↗

Reduced Filaggrin expression induces dysregulated intracellular signalling in atopic eczemaSemantic proximity Read ↗

Filaggrin loss-of-function mutations, atopic dermatitis and risk of actinic keratosis: results from two cross-sectional studies.Semantic proximity Read ↗

Common filaggrin gene loss-of-function variants are associated with skin cancer risk.Semantic proximity Read ↗

Associations of filaggrin gene loss-of-function variants and human papillomavirus-related cancer and pre-cancer in Danish adults.Semantic proximity Read ↗

Filaggrin genotype in ichthyosis vulgaris predicts abnormalities in epidermal structure and function.Semantic proximity Read ↗

Filaggrin Mutation in Korean Patients with Atopic Dermatitis.Semantic proximity Read ↗

Delineation of diversified desmoglein distribution in stratified squamous epithelia: implications in diseasesSemantic proximity Read ↗

Focal adhesion complex proteins in epidermis and squamous cell carcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.