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Article

Associations of filaggrin gene loss-of-function variants and human papillomavirus-related cancer and pre-cancer in Danish adults.

PloS one - 1 Jan 2014

Skaaby Tea, Husemoen Lise Lotte N, Jørgensen Torben, Johansen Jeanne D, Menné Torkil, Szecsi Pal B, Stender Steen, Bager Peter, Thyssen Jacob P, Linneberg Allan

Abstract excerpt

PURPOSE: Filaggrin proteins are expressed in the skin, oral cavity, oesophagus, and cervical mucose. Loss-of-function mutations in the filaggrin gene (FLG) reduce filaggrin expression and cause an impaired skin barrier function. We hypothesized that FLG mutation carriers would be more susceptible...

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Source

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Identifiers

PMID: 24905740
DOI: 10.1371/journal.pone.0099437
PMCID: PMC4048243

Genes

FLG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24905740-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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