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Article

Association of SLC6A4 methylation with long-term outcomes after stroke: focus on the interaction with suicidal ideation.

Scientific reports - 1 Feb 2021

Kang Hee-Ju, Lee Eun-Hye, Kim Ju-Wan, Kim Sung-Wan, Shin Il-Seon, Kim Joon-Tae, Park Man-Seok, Cho Ki-Hyun, Han Jung-Soo, Lyoo In Kyoon, Kim Jae-Min

Abstract excerpt

Serotonin (5-HT) plays an important role in cerebrovascular homeostasis and psychiatric disorders, including suicidality. Methylation of the serotonin transporter gene (SLC6A4) is associated with 5-HT expression. However, the prognostic roles of SLC6A4 methylation and suicidal ideation (SI) in long-term outcomes of stroke have not been evaluated. We investigated the independent and interactive effects of SLC6A4...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33526821
DOI: 10.1038/s41598-021-81854-9
PMCID: PMC7851135

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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