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Article

Associations of B-Type Natriuretic Peptide and Its Coding Gene Promoter Methylation With Functional Outcome of Acute Ischemic Stroke: A Mediation Analysis.

Journal of the American Heart Association - 15 Sept 2020

Wang Aili, Zhang Mingzhi, Ding Yi, Mo Xingbo, Zhong Chongke, Zhu Zhengbao, Guo Daoxia, Zheng Xiaowei, Xu Tan, Liu Yan, Zhang Yonghong, Peng Hao

Abstract excerpt

Background The prognostic role of B-type natriuretic peptide (BNP) in stroke has been suggested, but limited studies have shown mixed results and unknown underlying mechanisms. DNA methylation, a molecular modification that alters gene expression, may represent a candidate mechanism for this purpose. We aimed to examine the associations of BNP and methylation of its coding gene (natriuretic peptide B [NPPB]) with...

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Share to DNA Methylation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Ischemic Stroke

Share to Natriuretic Peptide, Brain

Share to Promoter Regions, Genetic

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Source

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Identifiers

PMID: 32875935
DOI: 10.1161/JAHA.120.017499
PMCID: PMC7727007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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