Article
Serotonin transporter gene expression predicts the worsening of suicidal ideation and suicide attempts along a long-term follow-up of a Major Depressive Episode.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Mar 2018
Consoloni Julia-Lou, Ibrahim El Chérif, Lefebvre Marie-Noëlle, Zendjidjian Xavier, Olié Emilie, Mazzola-Pomietto Pascale, Desmidt Thomas, Samalin Ludovic, Llorca Pierre-Michel, Abbar Mocrane, Lopez-Castroman Jorge, Haffen Emmanuel, Baumstarck Karine, Naudin Jean, Azorin Jean-Michel, El-Hage Wissam, Courtet Philippe, Belzeaux Raoul
Abstract excerpt
The quest for biomarkers in suicidal behaviors has been elusive so far, despite their potential utility in clinical practice. One of the most robust biological findings in suicidal behaviors is the alteration of the serotonin transporter function in suicidal individuals. Our main objective was to investigate the predictive value of the serotonin transporter gene expression (SLC6A4) for suicidal ideation and as...
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