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Article

A longitudinal study of SLC6A4 DNA promoter methylation and poststroke depression.

Journal of psychiatric research - 1 Sept 2013

Kim Jae-Min, Stewart Robert, Kang Hee-Ju, Kim Sung-Wan, Shin Il-Seon, Kim Hye-Ran, Shin Myung-Geun, Kim Joon-Tae, Park Man-Seok, Cho Ki-Hyun, Yoon Jin-Sang

Abstract excerpt

Serotonin transporter gene (SLC6A4) has been shown to play an important role in the pathophysiology of mood disorders including poststroke depression (PSD). SLC6A4 expression is influenced by DNA methylation status and the SLC6A4 linked promoter region (5-HTTLPR) polymorphism. This study aimed to investigate whether SLC6A4 methylation status was associated with depression ascertained at two weeks and one year...

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Source

Identifiers

PMID: 23702251
DOI: 10.1016/j.jpsychires.2013.04.010

Genes

PSD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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