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Article

Effect of Trinucleotide Repeats in the Huntington's Gene on Intelligence

30 Mar 2018

Abstract excerpt

BACKGROUND: Huntington's Disease (HD) is caused by an abnormality in the HTT gene. This gene includes trinucleotide repeats ranging from 10 to 35, and when expanded beyond 39, causes HD. We previously reported that CAG repeats in the normal range had a direct and beneficial effect on brain development with higher repeats being associated with higher cognitive function. The current study now expands this line of...

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PMID: 29685790
DOI: 10.1016/j.ebiom.2018.03.031

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