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Article

Are cognitive changes progressive in prediagnostic HD?

Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology - 1 Dec 2007

Stout Julie C, Weaver Marjorie, Solomon Andrea C, Queller Sarah, Hui Siu, Johnson Shannon A, Gray Jacqueline, Beristain Xabier, Wojcieszek Joanne, Foroud Tatiana

Abstract excerpt

OBJECTIVE: To characterize neurocognitive signs of disease progression in prediagnosis and early Huntington disease (HD) and compare the sensitivity of 2 disease staging classification schemes for detecting these signs. METHODS: Three hundred and six individuals at-risk for or recently diagnosed with HD completed the Unified Huntington's Disease Rating Scale, genetic testing, and a neurocognitive battery. Two...

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PMID: 18091069
DOI: 10.1097/WNN.0b013e31815cfef8

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