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Article

Longitudinal cognitive and motor changes among presymptomatic Huntington disease gene carriers.

Archives of neurology - 1 May 1999

Kirkwood S C, Siemers E, Stout J C, Hodes M E, Conneally P M, Christian J C, Foroud T

Abstract excerpt

OBJECTIVE: To determine whether longitudinal changes in cognitive and motor function can be detected among clinically presymptomatic individuals carrying the Huntington disease (HD) allele. DESIGN: A longitudinal, case-control, double-blind study comparing presymptomatic gene carriers and non-gene carriers at risk for HD examined an average of 3.7 years apart. SETTING: The Department of Medical and Molecular...

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Identifiers

PMID: 10328251
DOI: 10.1001/archneur.56.5.563

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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