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Article

Chromatin conformation changes in peripheral blood can detect prostate cancer and stratify disease risk groups

28 Jan 2021

Abstract excerpt

BACKGROUND: Current diagnostic blood tests for prostate cancer (PCa) are unreliable for the early stage disease, resulting in numerous unnecessary prostate biopsies in men with benign disease and false reassurance of negative biopsies in men with PCa. Predicting the risk of PCa is pivotal for making an informed decision on treatment options as the 5-year survival rate in the low-risk group is more than 95% and...

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PMID: 33509203
DOI: 10.1186/s12967-021-02710-y

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