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Article

Novel germline TRAF3IP3 mutation in a dyad with familial acute B lymphoblastic leukemia.

Cancer reports (Hoboken, N.J.) - 1 Jun 2021

Pommert Lauren, Burns Robert, Furumo Quinlan, Pulakanti Kirthi, Brandt Jon, Burke Michael J, Rao Sridhar

Abstract excerpt

BACKGROUND: Acute lymphoblastic leukemia (ALL) is the most common hematologic malignancy in children, representing 25% of all new cancer diagnoses. Advances in genomic sequencing have demonstrated that inherited genetic risk factors play a larger role in leukemia development than previously appreciated. AIM: We identified a father-daughter dyad with childhood B-cell ALL and aimed to investigate whether the pair...

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Identifiers

PMID: 33503336
DOI: 10.1002/cnr2.1335
PMCID: PMC8222551

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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