Article
Autoimmunity in women: an eXamination of eXisting models.
Clinical immunology (Orlando, Fla.) - 1 Jan 2020
Yuen Grace J
Abstract excerpt
Women comprise over 80% of the affected individuals for many autoimmune conditions. Although sex-specific differences in sex hormones are thought to contribute to the female predisposition to autoimmunity, emerging evidence also suggests an intriguing role of both physiological and dysregulated X-chromosome inactivation. Furthermore, recent studies have demonstrated that many immune genes encoded on the X...
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