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Characteristics of Epigenetic Clocks Across Blood and Brain Tissue in Older Women and Men

7 Jan 2021

Abstract excerpt

Epigenetic clocks are among the most promising biomarkers of aging. It is particularly important to establish biomarkers of brain aging to better understand neurodegenerative diseases. To advance application of epigenetic clocks—which were largely created with DNA methylation levels in blood samples—for use in brain, we need clearer evaluation of epigenetic clock behavior in brain, including direct comparisons of...

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Dementia and Cognitive Impairment Research
Epigenetics and DNA Methylation

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33488342
DOI: 10.3389/fnins.2020.555307

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