Article

Changes in the cerebrospinal fluid proteome precede and stratify the course of Parkinson’s Disease

2022-06-09

Abstract excerpt

The proteome encodes for various information. By quantifying 4071 human proteins in the cerebrospinal fluid using high-throughput affinity proteomics, this study aimed to extract proteomic signatures associated with Parkinson’s disease using unbiased machine-learning and to examine their impact on Parkinson’s disease course. From the Parkinson’s Progression Markers Initiative, we first included 312 drug-naïve pati...

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Identifiers and source

Literature Corpus work: ac790f88-71fe-5639-84da-c3ddb83439a6
DOI: 10.1101/2022.06.08.22276035

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