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Four novel BRCA variants found in Chinese hereditary breast cancer patients by next-generation sequencing.

Clinica chimica acta; international journal of clinical chemistry - 1 May 2021

Liu Peng-Fei, Zhuo Zhong-Ling, Xie Fei, Wang Shu, Zhao Xiao-Tao

Abstract excerpt

Breast cancer is the most frequent cancer among women worldwide. Patients carrying mutations in breast cancer susceptibility genes like BRCA1 and BRCA2 (BRCA1/2) account for 5-10% of all breast cancer patients. Therefore, screening for susceptibility genes may reduce the incidence of breast cancer and improve prognosis. To provide evidence for mutation interpretation and targeted drug use in breast cancer...

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PMID: 33476590
DOI: 10.1016/j.cca.2021.01.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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