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Article

Therapeutic considerations for APOE and TOMM40 in Alzheimers disease: A tribute to Allen Roses MD.

Expert opinion on investigational drugs - 1 Jan 2021

Sabbagh Marwan Noel, Pope Evans, Cordes Laura, Shi Jiong, DeCourt Boris

Abstract excerpt

Introduction: Four years ago this Autumn, pioneering neurologist Prof. Allen. D. Roses passed away. Hence, we have taken time to reflect on his work and legacy in Alzheimer's disease (AD) research. Prof. Roses rejected the widely accepted amyloid hypothesis, which identifies amyloid beta (Aβ) protein accumulation within the brain as the cause of AD. Instead, he proposed that the epsilon type 4 allele of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33455481
DOI: 10.1080/13543784.2021.1849138
PMCID: PMC9262379

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