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Article

The Interplay between HGF/c-met Axis and Nox4 in BRAF Mutated Melanoma.

International journal of molecular sciences - 13 Jan 2021

Beretti Francesca, Farnetani Francesca, Reggiani Bonetti Luca, Fabbiani Luca, Zavatti Manuela, Maiorana Antonino, Pellacani Giovanni, Maraldi Tullia

Abstract excerpt

BACKGROUND: Melanoma is the leading cause of death due to cutaneous malignancy and its incidence is on the rise. Several signaling pathways, including receptor tyrosine kinases, have a role in the development and progression of melanocytic lesions and malignant melanoma. Among those, the hepatocyte growth factor (HGF)/c-met axis is emerging as a critical player because it can play a role in drug resistance....

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Source

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Identifiers

PMID: 33451139
DOI: 10.3390/ijms22020761
PMCID: PMC7828605

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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