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Article

Role of the HGF/c-MET tyrosine kinase inhibitors in metastasic melanoma

15 Feb 2018

Abstract excerpt

Metastatic disease in a cancer patient still remains a therapeutic challenge. Metastatic process involves many steps, during which malignant cells succeed to activate cellular pathways promoting survival in hostile environment, engraftment and growth at the distant site from the primary tumor. Melanoma is known for its high propensity to produce metastases even at the early stages of the disease. Here we...

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PMID: 29455657
DOI: 10.1186/s12943-018-0795-z

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