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Article

Alterations observed in the interferon α and β signaling pathway in MDD patients are marginally influenced by cis-acting alleles.

Scientific reports - 12 Jan 2021

Magri Chiara, Giacopuzzi Edoardo, Sacco Chiara, Bocchio-Chiavetto Luisella, Minelli Alessandra, Gennarelli Massimo

Abstract excerpt

Major depressive disorder (MDD) is a common psychiatric disorder with a multifactorial aetiology determined by the interaction between genetic and environmental risk factors. Pieces of evidence indicate that inflammation and immune activation may contribute to the onset of MDD playing a role in the pathogenetic mechanism. To date, it is not known to which extent the association between MDD and inflammation is...

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Identifiers

PMID: 33436853
DOI: 10.1038/s41598-020-80374-2
PMCID: PMC7804189

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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