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Association study of polymorphisms within inflammatory genes and methylation status in treatment response in major depression

14 May 2019

Abstract excerpt

BACKGROUND: Although pharmacogenetics for major depressive disorder (MDD) is gaining momentum, the role of genetics in differences in response to antidepressant treatment is controversial, as they depend on multifactorial and polygenic phenotypes. Previous studies focused on the genes of the serotonergic system, leaving apart other pathological factors such as the inflammatory pathway. The main objective of the...

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PMID: 31100612
DOI: 10.1016/j.eurpsy.2019.05.003

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