Article
Gene × environment interactions in the prediction of response to antidepressant treatment.
The international journal of neuropsychopharmacology - 1 Apr 2013
Klengel Torsten, Binder Elisabeth B
Abstract excerpt
Major depressive disorder (MDD) is responsible for an increasing individual and global health burden. Extensive research on the genetic disposition to develop MDD and to predict the response to antidepressant treatment has yet failed to identify strong genetic effects. The concept of gene × environment interaction takes into account that environmental factors have been identified as important components in the...
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