Article
Type I interferon signaling genes in recurrent major depression: increased expression detected by whole-blood RNA sequencing.
Molecular psychiatry - 1 Dec 2014
Mostafavi S, Battle A, Zhu X, Potash J B, Weissman M M, Shi J, Beckman K, Haudenschild C, McCormick C, Mei R, Gameroff M J, Gindes H, Adams P, Goes F S, Mondimore F M, MacKinnon D F, Notes L, Schweizer B, Furman D, Montgomery S B, Urban A E, Koller D, Levinson D F
Abstract excerpt
A study of genome-wide gene expression in major depressive disorder (MDD) was undertaken in a large population-based sample to determine whether altered expression levels of genes and pathways could provide insights into biological mechanisms that are relevant to this disorder. Gene expression studies have the potential to detect changes that may be because of differences in common or rare genomic sequence...
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