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Article

A class I odorant receptor enhancer shares a functional motif with class II enhancers.

Scientific reports - 12 Jan 2021

Iwata Tetsuo, Tomeoka Satoshi, Hirota Junji

Abstract excerpt

In the mouse, 129 functional class I odorant receptor (OR) genes reside in a ~ 3 megabase huge gene cluster on chromosome 7. The J element, a long-range cis-regulatory element governs the singular expression of class I OR genes by exerting its effect over the whole cluster. To elucidate the molecular mechanisms underlying class I-specific enhancer activity of the J element, we analyzed the J element sequence to...

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Topics

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Share to Amino Acid Motifs
Share to Chromosomes, Human, Pair 7
Share to Enhancer Elements, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression

Share to Homeodomain Proteins

Share to Olfactory Mucosa

Share to Receptors, Odorant

Source

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Identifiers

PMID: 33436797
DOI: 10.1038/s41598-020-79980-x
PMCID: PMC7804114

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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